4 December 21, 2015
1. Eaman A. S. AL-Rubaee, Suha T. Abd, Nadia M. Kadim
The Effect of Titanium Dioxide Nanoparticles on Salivary Alkaline Phosphatase Activity
European Journal of Molecular Biotechnology, 2015, Vol.(10), Is. 4, pp. 188-196.
Number of views: 2446 Download in PDF
2. Ignat Ignatov, Oleg MosinEuropean Journal of Molecular Biotechnology, 2015, Vol.(10), Is. 4, pp. 188-196.
Abstract:
The structural and optical properties of the titanium dioxide nanoparticles [TiO2 NPs] have been investigated using [UV-Vis] spectrophotometer and SEM. The produced nanoparticles show small and about sharp round peaks around 220 nm. The produced nanoparticles have a spherical shape with an average particle size ˂50 nm. The effect of titanium dioxide NPs was studied on the activity of Alkaline Phosphatase [ALP] in the saliva of 25 patients with gingivitis in comparison to 20 healthy subjects with the average age about 22–23 years for both groups. The results correlated with the observation that salivary alkaline phosphatase activity increase in patient with gingivitis in comparison to control group and salivary ALP activity inhibited by titanium dioxide nanoparticles.
The structural and optical properties of the titanium dioxide nanoparticles [TiO2 NPs] have been investigated using [UV-Vis] spectrophotometer and SEM. The produced nanoparticles show small and about sharp round peaks around 220 nm. The produced nanoparticles have a spherical shape with an average particle size ˂50 nm. The effect of titanium dioxide NPs was studied on the activity of Alkaline Phosphatase [ALP] in the saliva of 25 patients with gingivitis in comparison to 20 healthy subjects with the average age about 22–23 years for both groups. The results correlated with the observation that salivary alkaline phosphatase activity increase in patient with gingivitis in comparison to control group and salivary ALP activity inhibited by titanium dioxide nanoparticles.
Number of views: 2446 Download in PDF
S. Miller’s Experiments in Modelling of Non-Equilibrium Conditions with Gas Electric Discharge Simulating Primary Atmosphere
European Journal of Molecular Biotechnology, 2015, Vol.(10), Is. 4, pp. 197-209.
Number of views: 2109 Download in PDF
3. Ignat Ignatov, Oleg MosinEuropean Journal of Molecular Biotechnology, 2015, Vol.(10), Is. 4, pp. 197-209.
Abstract:
In this paper are submited data on the possibility of applying the coronal gas discharge effect (CGDE) in modeling non-equilibrium conditions with gas electric discharge simulating conditions occurying in the primary atmosphere (electric sparks, lightning) imitating S. Miller’s experiments. The physical basis and technique of visualization of gas discharge (GD) glowing of water drops in alternating electric fields of high electrical voltage (5–30 kV) and frequency (10–150 kHz), as well as the possible electrosynthesis of organic molecules from a mixture of inorganic substances as hydrogen (H2), methane (CH4), ammonia (NH3) and carbon monoxide (CO) in aqueous solutions of water exposed under the electrical discharge, UV-radiation and thermal heating to t = +100 0C were examined. The colour coronal spectral gas discharge analysis was applied for investigation of water samples of various origin, the samples of hot mineral, sea and mountain water obtained from various water sources of Bulgaria.
In this paper are submited data on the possibility of applying the coronal gas discharge effect (CGDE) in modeling non-equilibrium conditions with gas electric discharge simulating conditions occurying in the primary atmosphere (electric sparks, lightning) imitating S. Miller’s experiments. The physical basis and technique of visualization of gas discharge (GD) glowing of water drops in alternating electric fields of high electrical voltage (5–30 kV) and frequency (10–150 kHz), as well as the possible electrosynthesis of organic molecules from a mixture of inorganic substances as hydrogen (H2), methane (CH4), ammonia (NH3) and carbon monoxide (CO) in aqueous solutions of water exposed under the electrical discharge, UV-radiation and thermal heating to t = +100 0C were examined. The colour coronal spectral gas discharge analysis was applied for investigation of water samples of various origin, the samples of hot mineral, sea and mountain water obtained from various water sources of Bulgaria.
Number of views: 2109 Download in PDF
Studying the hydrological conditions for origin of first organic forms of life in hot mineral water with HDO
European Journal of Molecular Biotechnology, 2015, Vol.(10), Is. 4, pp. 210-227.
Number of views: 2156 Download in PDF
4. Angelina O. ZekiyEuropean Journal of Molecular Biotechnology, 2015, Vol.(10), Is. 4, pp. 210-227.
Abstract:
The isotopic composition, the temperature and the pH value of water were analyzed in experiments with prognosis of primary hydrosphere and hydrological conditions for origin of first organic forms in hot mineral water with HDO. For this aim we performed experiments with hot mineral water and seawater from Bulgaria and water with varying content of deuterium using IR- and DNES-spectroscopy. As model systems were used cactus juice of Echinopsis pachanoi and Mediterranean jellyfish Cotylorhiza tuberculata. The reactions of condensation–dehydration occurring in alkaline aqueous solutions at t = 65–95 0C and рН = 9–10, resulting in synthesis from unorganic molecules the larger organic molecules as polymers and short polipeptides, were discussed, as well as the possible mechanisms of the deuterium accumulation in form of HDO in hot water. It was shown that hot alkaline mineral water with temperature from +65 0C to +95 0C and the pH value from 9 to 11 is more suitable for the origination of life and living matter than other analyzed water samples. In hot mineral waters the local maximums in IR-spectra are more manifested compared to the local maximums obtained in IR-spectra of the same water at a lower temperature. The difference in the local maximums from +20 0C to +95 0C at each +5 0C according to the Student t-criterion makes up p < 0,05.
The isotopic composition, the temperature and the pH value of water were analyzed in experiments with prognosis of primary hydrosphere and hydrological conditions for origin of first organic forms in hot mineral water with HDO. For this aim we performed experiments with hot mineral water and seawater from Bulgaria and water with varying content of deuterium using IR- and DNES-spectroscopy. As model systems were used cactus juice of Echinopsis pachanoi and Mediterranean jellyfish Cotylorhiza tuberculata. The reactions of condensation–dehydration occurring in alkaline aqueous solutions at t = 65–95 0C and рН = 9–10, resulting in synthesis from unorganic molecules the larger organic molecules as polymers and short polipeptides, were discussed, as well as the possible mechanisms of the deuterium accumulation in form of HDO in hot water. It was shown that hot alkaline mineral water with temperature from +65 0C to +95 0C and the pH value from 9 to 11 is more suitable for the origination of life and living matter than other analyzed water samples. In hot mineral waters the local maximums in IR-spectra are more manifested compared to the local maximums obtained in IR-spectra of the same water at a lower temperature. The difference in the local maximums from +20 0C to +95 0C at each +5 0C according to the Student t-criterion makes up p < 0,05.
Number of views: 2156 Download in PDF
Molecular Approaches to Functionalization of Dental Implant Surfaces
European Journal of Molecular Biotechnology, 2015, Vol.(10), Is. 4, pp. 228-240.
Number of views: 2186 Download in PDF
5. European Journal of Molecular Biotechnology, 2015, Vol.(10), Is. 4, pp. 228-240.
Abstract:
The present review examines several approaches to improve properties of dental implants by modifying their bioactive surfaces (functionalization) using the techniques of molecular transplantation. The first group of functional ligands is designed to enhance osseointegration of implants, it includes growth factors, promoting the formation and bone remodeling: bone morphogenetic proteins (BMPs), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF) and their combinations with each other, and several other ones. The second group of bioactive molecules does not directly stimulate bone formation, but it promotes osteoblast seeding on the implant surface due to the adhesive properties, thus accelerating osseointegration. Finally, the third group of substances used to increase the antibacterial properties of coatings, thereby reducing the formation of bacterial film on the implant surface and the risk of inflammatory rejection of the implant. Key issues of using biofunctional coatings, despite their obvious promise today still are relatively high cost, difficulties of controlling properties and its storage between the fabrication and installation of implants in the bone of the recipient.
The present review examines several approaches to improve properties of dental implants by modifying their bioactive surfaces (functionalization) using the techniques of molecular transplantation. The first group of functional ligands is designed to enhance osseointegration of implants, it includes growth factors, promoting the formation and bone remodeling: bone morphogenetic proteins (BMPs), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF) and their combinations with each other, and several other ones. The second group of bioactive molecules does not directly stimulate bone formation, but it promotes osteoblast seeding on the implant surface due to the adhesive properties, thus accelerating osseointegration. Finally, the third group of substances used to increase the antibacterial properties of coatings, thereby reducing the formation of bacterial film on the implant surface and the risk of inflammatory rejection of the implant. Key issues of using biofunctional coatings, despite their obvious promise today still are relatively high cost, difficulties of controlling properties and its storage between the fabrication and installation of implants in the bone of the recipient.
Number of views: 2186 Download in PDF